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The Chemical Aspects of The Origin of Life

"Life is the cumulative product of interactions among the many kinds of chemical substances that make up the cells of an organism."
-- Neil A. Campbell

People once believed that bacteria could spring spontaneously from non-living things, which was later proven "wrong" by Pasteur with his famous twitched-neck flask experiment. Ironically, today, we've realized that the very first life on Earth was indeed originated from abiotic surroundings. In fact, organic molecules have been successfully generated from abiotic elements by scientists Miller and Urey.

The abiotic chemical evolution of life follows 4 major steps:

1. the abiotic synthesis and accumulation of small organic molecules, or monomers, such as amino acids and nucleotides;
2. the joining of these monomers into polymers, including proteins and nucleic acids;
3. the aggregation of abiotically produced molecules into droplets, protobionts, that had chemical characteristics different from their surroundings; and
4. the origin of heredity. (Campbell)

To understand how this creation of life from abiotic material occured, we have to consider 2 critical ideas (F. Shu):
1. The extension of the idea of natural selection to chemical level.
2. The realization that the condition of the early Earth when life first arose must have been vastly different from present:
a) non-oxidizing atmosphere: present level of oxygen, which began to accumulate around 2.1 billion years ago with the presence of cyanobacteria, would have been lethal to primitive organisms
b) abundant resources produced non-biologically
c) long time scale without competition


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